When using the Run Optimizer button, a few things are worth noting.

• The optimum found may not be optimal for you… The optimizer tries to fit the impedance curve under the target with as few capacitors as possible. Or actually capacitor cost as you can set a relative cost of each capacitor type as well.
• There is some randomness to the optimizer, so you may not find the same “optimum” solution in two runs. Try a few times to find something you like.
• Lines where the QTY value is zero are not considered. So if you want to have the optimizer try to use all the capacitor types you have defined, make sure QTY is at least one for all of them.

For difficult problems, it makes sense to find an approximate solution manually first before starting the optimizer. Another technique is to start with an easier (higher) target impedance and then gradually lower it for each run of the optimizer.